Julia Pumas Ai

A team of scientists and scientfic computing experts

  • helping pharmaceutical scientists, healthcare providers, biotechnology, and pharmaceutical companies deliver better treatments to patients faster

    Products

    • Pumas Pharmaceutical Modeling And Simulation
      • it is a suite of tools used to perform quantitative analytics of various kinds
        • across pharmaceutical drug development
      • provides efficient implementations of all aspects of the analytics
        • in this domain under one cohesive package
    • DeepPumas Neural-network infrastructure for SciML models (designed for the healthcare industry)
      • of longitudinal data
        • e.g. pharmaceutical modeling,
          • while leveraging the non-linear mixed effects (NLME) functionality
      2 ways of enhancing Pumas models with ML
      • Embedding Neural Networks directly in a `@model`
      • predicting a part of individual variability from baseline covariates via neural networks
    • PumasCP Clinical Pharmacology Analysis & Reporting Tool
      • Bioequivalence Analysis
      • Toxicokinectic Analysis
      • Non-compartmental Analysis
      Pumas is the only software that matches SAS for BE anaylsis

Competitors

  • Monolix:
    • most advanced and easy-to-use solution for non-linear mixed effects modeling (NLME) for pharmacometrics.
    • It is based on the SAEM algorithm to provide robust, global convergence even for complex models,
      • and is equipped with a user-friendly interface to ensure a simple and fast workflow.
  • NONMEM:
    • non-linear mixed-effects modeling software package 1970s
      • and expanded at Icon PLC. Its name is an acronym for nonlinear mixed effects modeling
    • but it is especially powerful in the context of
      • population
      • pharmacokinetics,
      • pharmacometrics,
      • PK/PD models
    • NONMEM models are written in NMTRAN,
      • a dedicated model specification language that is translated into FORTRAN
        • compiled on the fly
          • and executed by a command-line script.
  • Phoenix WinNonlin:
    • analysis of pharmacokinetic and pharmacodynamics
    • integrated tools for
      • data processing,
      • non-compartmental analysis(NCA),
      • PK/PD modeling,
      • post-analysis statistics,
      • table creation,
      • graphics
    • from early non-clinical research to large clinical trials
      • the NCA engine, individual PK/PD modeling engine, and statistical analysis tools
        • can be used for a wide-range of studies and analyses